Acute kidney injury (AKI) kills 2 million people every year. In AKI, kidney function fails suddenly and may later recover spontaneously. However there is no treatment that accelerates recovery and patients may require replacement of renal function by dialysis.

Kidney Attack aims to change this status quo by innovative and smart combination of scientific literature, preclinical and clinical studies that explore multiple markers (i.e. systems biology, omics) to propose early personalized detection of AKI and novel treatments.

For this:

  1. We will move from a single marker of early AKI to multiple markers that better capture the complexity of human disease
  2. We will develop a humanized version of this multiple marker panel
  3. We will use the humanized version of the multiple marker panel to search for new treatments that may be personalized based on the multiple markers