The PRECISE-HEART module is a 4-week, 20-hour online course designed to educate healthcare professionals on the integration of personalised medicine in cardiovascular care. It covers genomics, multi-omics, biomarkers, AI, digital tools, and emerging therapies, alongside ethical, legal, and policy considerations. The course aims to equip clinicians, researchers, and students with the skills to interpret genetic data, apply precision diagnostics, and implement tailored treatments. Through interactive case studies, simulations, and expert-led content, participants will develop competencies in clinical decision-making, interdisciplinary collaboration, and patient communication, ultimately fostering the adoption of personalised approaches in cardiovascular practice across Europe.