The European Commission has published a draft amendment to the Horizon Europe Work Programme 2026-2027, Part 4: Health, through the Comitology Register. The draft includes several potential 2027 call topics of interest to the personalised medicine community.
Please note that the document is a draft and has not been adopted or endorsed by the European Commission. The call topics, budgets, opening dates and deadlines may still change. Applicants should therefore wait for the official publication of the work programme and the corresponding call pages on the EU Funding & Tenders Portal before preparing or submitting proposals.
Potential topics to watch:
| Topic | Call Timing | Budget / Action Type |
|---|---|---|
| HORIZON-HLTH-2027-01-CARE-02: Personalised approaches to reduce risks from Adverse Drug Reactions due to administration of multiple medications | Opens 29 Oct 2026; deadline 17 Feb 2027, 17:00 Brussels time | RIA, EUR 38 million total; EUR 8–10 million per project |
| HORIZON-HLTH-2027-02-TOOL-01-two-stage: Development of predictive biomarkers of disease progression and treatment response by using AI methodologies for chronic non-communicable diseases | Opens 29 Oct 2026; first-stage deadline 17 Feb 2027, second-stage deadline 16 Sep 2027, 17:00 Brussels time | RIA, EUR 44.2 million total; EUR 6–8 million per project |
| HORIZON-HLTH-2027-03-TOOL-04: Virtual Human Twins for integrated clinical decision support in prevention and diagnosis | Opens 3 Jun 2027; deadline 16 Sep 2027, 17:00 Brussels time | RIA, EUR 39.3 million total; EUR 10–12 million per project |
| HORIZON-HLTH-2027-02-IND-02-two-stage: Portable and versatile Point-of-care diagnostics | Opens 29 Oct 2026; first-stage deadline 17 Feb 2027, second-stage deadline 16 Sep 2027, 17:00 Brussels time | IA, EUR 39.3 million total; EUR 5–7 million per project |
| HORIZON-HLTH-2027-02-DISEASE-01-two-stage: Innovative healthcare interventions for non-communicable diseases | Opens 29 Oct 2026; first-stage deadline 17 Feb 2027, second-stage deadline 16 Sep 2027 | RIA, EUR 63.8 million total; EUR 7–8 million per project |
| HORIZON-HLTH-2027-03-TOOL-08: Towards the next generation of frontier Artificial Intelligence models for healthcare | Opens 3 Jun 2027; deadline 16 Sep 2027 | CSA, EUR 2.9 million total |