EP PerMed JTC2025 Pre-announcement – Pharmacogenomic Strategies for Personalised Medicine (PGxPM2025)

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The European Partnership for Personalised Medicine, EP PerMed (supported by the European Union under Horizon Europe, Grant Agreement N° 101137129), is a platform for joint programming of national and European regional research and innovation supporting activities putting into action “The Strategic Research & Innovation Agenda (SRIA) for Personalised Medicine (2023)” , SRIA for PM (2023), through dedicated research, development and innovation funding.

EP PerMed funding organisations, listed below, have agreed to launch the joint transnational call 2025 (JTC2025), co-funded by the EU, to fund multinational innovative research projects in personalised medicine (PM), which should bring together academic, clinical/public health and private research teams, thus enhancing the competitiveness in Europe in this field. The JTC2025 will be conducted simultaneously by the participating funding organisations in their respective region/country and coordinated centrally by the Joint Call Secretariat (JCS), hosted by the German Aerospace Center e.V. – Project Management Agency, (DLR-PT), Germany.

The call will be implemented in two stages, i.e. a pre- and a full-proposal phase. The available budget for this call is 35 Mio. € (approx.).

An information day introducing the JTC2025 to the research community will be organised most probably on January 09, 2025. More details (including the registration) will follow soon.

DateAction
Mid of December, 2024Publication of the call
09 January 2025JTC2025 information day
18 February 2025 (14:00 CET)Deadline for pre-proposal submission
Expected around 16 May 2025Communication of the results of the pre-proposal assessment and invitation to the full-proposal stage
17 June 2025 (14:00, CEST)Deadline for full-proposal submission
Mid/end of August 2025Rebuttal stage
Expected for October 2025Communication of the funding decisions to the applicants
End of 2025, beginning of 2026Expected project start (according to regional/national funding regulations)
Expected timeline of the call

Aims of the Call

The overall objectives of the JTC2025 will be to

  • Support research projects in human health on pharmacogenomic strategies for personalised medicine approaches that address one or more of the following aspects:
    • identification of new pharmacogenomic markers or signatures using (multi)-omics data in relation to drug or drug combination.
    • validation of a pharmacogenomic marker or signatures using (multi)-omics data in predicting drug or drug combination outcomes.
    • use pharmaco-omics strategies to determine the right dosage, the efficacy of treatments and/or the risk of adverse drug response and non-response to treatment to tailor personalised treatment pathways, including combined treatments (multi-medication).
  • Encourage and enable interdisciplinary collaborations, i.e. multi-actor research by engaging a range of other relevant disciplines such as pre-clinical and clinical research, bioinformatics/health informatics/data research, ELSA research, implementation research or health economics research connected to the proposed research topic, including end-user perspective analysis to support the implementation of the research outcomes into clinical practice.
  • Encourage cross-sectorial collaborations, by including the private sector (e.g. SMEs, small and medium-sized enterprises), industry, as well as regulatory/HTA agencies and patient organisations.
  • Establish participatory research, i.e. active representation of patients or citizens as part of research projects.

Research projects in all disease areas will be welcome.

General (Eligibility) Conditions for Application

Whilst applications will be submitted jointly by groups from several countries, the individual applicants of each group will be funded by the respective regional/national EP PerMed funding organisation of the individual applicants. The applications are therefore subject to eligibility criteria and regulations of individual funding organisations. Applicants are strongly advised to contact their regional/ national representatives of the participating relevant funding organisation as soon as possible in order to confirm their eligibility (see also below “Contact details of participating members”).

Joint research proposals may be submitted by applicants belonging to the following categories (subject to regional/national funding regulations):

  1. Academia (research teams working in universities, other higher education institutions) or research institutes;
  2. Clinical/public health sector (research teams working in hospitals/public health and/or other healthcare settings and health organisations). Participation of clinicians (e.g. medical doctors, nurses) in the research teams is encouraged;
  3. Private for-profit (industry) partners, e.g. SME (small and medium-sized enterprises) and private non-profit partners, e.g. foundations, associations or non-governmental organisations.

More information about the eligibility criteria and rules regarding consortium composition will be available soon.

Partnering Tool

A new partnering tool developed and supported by the EP PerMed will be available for the call.

Participating Countries and European Regions

The following countries (23) are participating in the preparation of the call: Austria, Belgium, Czech Republic, Denmark, Estonia, Finland, France, Germany*, Greece, Hungary, Iceland, Ireland, Israel, Italy, Latvia, Lithuania, Luxembourg, Norway, Poland, Portugal, Spain, Sweden and Turkiye (contact list is provided below).

Besides national funders, the following regions are participating (10): Flanders (Belgium), Wallonia-Brussels Federation (Belgium), Saxony (Germany)*, Lombardy (Italy), Tuscany (Italy), Azores (Portugal), Centro Region (Portugal), Andalusia (Spain), Catalonia (Spain) and Navarre (Spain).

*decision on participation is still pending

Please note:

The information provided in this pre-announcement is indicative and may be subject to changes and is not legally binding to funding organisations. Additional funding organisations might join the call before the official publication or leave the funders consortium.

Interested applicants are encouraged to initiate scientific contacts with potential project consortium partners for applications. The final call information is expected to be published on the EP PerMed website in December 2024.

List of Regional/National Contacts

Name of participating organisationCountry/RegionRegional/National contact
Austrian Science Fund, (FWF)AustriaHannes Zwickl
hannes.zwickl@fwf.ac.at
Tel.: +43 676 83487 8219
The Research Foundation – Flanders, (FWO)Belgium (Flanders)Toon Monbaliu (FO)
Kristien Peeters (SBO) europe@fwo.be
Tel.: +32 (0)2 550 15 70
Tel.: +32 (0)2 550 15 95
Fund for Scientific Research – FNRS, (F.R.S.-FNRS)Belgium (Wallonia-Brussels Federation)Maxime Bonsir
international@frs-fnrs.be
Tel.: +32 2504 9236
The Ministry of Health of the Czech Republic / Czech Health Research Council, (MZCR/AZVCR)Czech RepublicMonika Kocmanova
Monika.kocmanova@azvcr.cz
Tel.: +420 606 273 871
Innovation Fund Denmark, (IFD)DenmarkKatrine Boeriis
katrine.boeriis@innofond.dk
internationale@innofond.dk
Tel.: +45 61 90 50 06
Estonian Ministry of Social Affairs, (MoSAE)EstoniaMari Teesalu
Mari.teesalu@sm.ee
Tel.: +372 5916 2047
Estonian Research Council, (ETAG)EstoniaMargit Suuroja
Margit.Suuroja@etag.ee
Tel.: +372 731 7360
Argo Soon
Argo.Soon@etag.ee
Tel.: +372 515 3424
Business Finland, (BFRK)FinlandNorma Jäppinen
norma.jappinen@businessfinland.fi
Matti Hiltunen
matti.hiltunen@businessfinland.fi
Tel.: +358 50 5577 012
Tel.: +358 50 5577 652
Agence Nationale de la Recherche, (ANR)FranceMonika Frenzel
Tel: (+33) (0) 1 73 54 83 32
EPPerMed@agencerecherche.fr
Federal Ministry of Education and
Research, (BMBF)
German Aerospace Center e.V. – Project Management Agency, (DLR)*
GermanyUte Preuss
Jacqueline Kalb
permed@dlr.de
Tel.: +49 228 3821-2211
Federal Ministry of Health, (BMG) German Aerospace Center e.V. – Project Management Agency, (DLR)GermanyComing soon
Saxon State Ministry for Science, Culture and Tourism, (SMWK)*Germany (Saxony)Coming soon
General Secretariat for Research & innovation, (GRST)Greece Coming soon
National Research, Development and Innovation Office, (NKFIH)HungaryZsuzsanna Kürti
nemzetkozi@nkfih.gov.hu
zsuzsanna.kurti@nkfih.gov.hu
Tel.: +36 70 375 0036
The Icelandic Centre for Research, (RANNIS)IcelandHelga Snævarr Kristjánsdóttir
Helga.s.kristjansdottir@rannis.is
Research Ireland, (RI)IrelandEmma McGrath
Emma.mcgrath@researchireland.ie
eu-Cofund@sfi.ie
Tel.: +353 86 1991351
Chief Scientist Office, Ministry of Health, (CSO-MOH)IsraelLiron Even-Faitelson
Liron.ef@moh.gov.il
Tel.: +972-2-5082168
Italian Ministry of Health, (IT-MoH)ItalyMaria Josefina Ruiz Alvarez
mj.ruizalvarez-esterno@sanita.it
Tel.: (+39) 06-4990 6836
Chiara Ciccarelli
c.ciccarelli@sanita.it
Tel.: (+39) 06-5994 3919
Fondazione Regionale per la Ricerca Biomedica, (FRRB)Italy (Lombardy)Giulia Maria Rossignolo
bandi@frrb.it
Tel.: +39 0267650159
Tuscany Region, (RT)Italy (Tuscany)Donatella Tanini
Teresa Vieri
eppermed@regione.toscana.it
Tel.: +39 055 4383256
Tel.: +39 055 4383289
Latvian Council of Science, (LZP)LatviaUldis Berkis
Uldis.Berkis@lzp.gov.lv
Tel.: +37129472349
Research Council of Lithuania, (LMT)LithuaniaŽivilė Ruželė
zivile.ruzele@lmt.lt
Tel.: (+370) 676 14383
Luxembourg National Research Fund (FNR)LuxembourgGideon Gießelmann
gideon.giesselmann@fnr.lu
Tel.: +352 691 362 805
The Research Council of Norway, (RCN)NorwayKatrine Rolid
karo@rcn.no
Tel.: +47 415 48 328
National Centre for Research and Development, (NCBR)PolandAnna Stępień
anna.stepien@ncbr.gov.pl
Tel.: +48 22 39 07 210
Fundação para a Ciência e a Tecnologia, (FCT)PortugalRita Cavaleiro
Pedro Ferreira
EPPerMed@fct.pt
Tel.: +351 213 911 541
Tel.: +351 213 924 445
Vice-Presidency of Azores Regional Government, (VP-GRA)Portugal (Azores)Maria Vale
Tel.: +351 296 308 922
Maria.LA.Vale@azores.gov.pt
Comissão de Coordenação e Desenvolvimento Regional do Centro, (CCDRC)Portugal (Centro Region)Sophie Patrício
Dora Cabete ccdrc.projects@ccdrc.pt
Tel.: +351 239400127
National Institute of Health Carlos III, (ISCIII)SpainMaría Callejo Arranz
mcallejo@isciii.es
Tel.: +34918222503
Consejería de Salud y Consumo de la Junta de Andalucía, (CSCJA)Spain (Andalusia)Alicia Milano Curto
ep.fps@juntadeandalucia.es
Health Department – Generalitat de Catalunya, (DS-CAT)Spain (Catalonia)Montserrat Llavayol
peris@gencat.cat
Tel.: +34 935566103
Government of Navarre, (CFN)Spain (Navarre)Javier Rodrigo
Javier.rodrigo.aznarez@navarra.es
Tel.: +34 848 42 76 69
Sweden´s Innovation Agency, (VINNOVA)*SwedenMalin Eklund
Malin.eklund@Vinnova.se
Tel.: +46 730 20 39 53
Casper Ullsten-Wahlund
casper.ullsten-wahlund@vinnova.se
Tel.: +46 730 20 51 25
The Scientific and Technological Research Council of Turkey, (TUBITAK)TurkiyeN. Selcan TÜRKER
selcan.turker@tubitak.gov.tr
Tel.: +90 312 298 1760
List of National Contacts

* Final decision for participation is still pending.